Considerations regarding the Implication of Polymorphic Variants and Chromosomal Inversions in Recurrent Miscarriage
نویسندگان
چکیده
Recurrent miscarriage becomes a problem that affect an increasing number of couples, almost 1% of the people who want to conceive. The aim of this study is to present the role of heterochromatic regions heteromorphism and chromosomal inversions in occurrence of recurrent miscarriage. In this study were included 354 couples with recurrent miscarriage, which presented at Medical Genetic Department of University of Medicine and Pharmacy Timisoara between octomber 2003 and november 2007. The most common findings were pericentric inversion of chromosome 9, heteromorphism of heterochromatic regions of chromosomes 1 and 16. Our date suggests that cytogeneticists should not ignore these variants that play an important role in reproduction failure.
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